Understanding the Assessment Criteria for Lymphoma and Chronic Lymphocytic Leukemia

History, Enhancements and Clarifications

This is an archived presentation.

While the assessment criteria for lymphoma and chronic lymphocytic leukemia are well accepted, the wide range of interpretations and applications has proved to be a challenge in clinical trials where consistent assessment across sites is critical to the validity of the data. This discussion will provide a historical overview from initial design to the basis for revision of the criteria. Clarifications for applying the revised criteria in clinical trials, with a particular emphasis on protocols and independent review analysis, will also be discussed.

By attending this webinar, you will:

  • Understand the rationale behind the development of the criteria
  • Increase your understanding and application of the criteria
  • Learn to harmonize site and independent review assessments of the criteria
  • Gain knowledge of misinterpretations in applying the criteria

Hear from the following experts:

Bruce D. Cheson, M.D.
Scientific Advisor
Perceptive Informatics

Dr. Bruce D. Cheson is Professor of Medicine, Head of Hematology and Director of Hematology Research at Georgetown University Hospital, Lombardi Comprehensive Cancer Center. He currently chairs the Lymphoma Committee of the Cancer and Leukemia Group B and the AJCC Subcommittee on Lymphoma. Previously, Dr. Cheson was Head of the Medicine Section for the National Cancer Institute's Clinical Investigations Branch within the Cancer Therapy Evaluation Program and senior staff physician in the NCI's Lymphoma Clinic. He has authored over 350 medical publications and abstracts on indications for AML, CLL, NHL and MDS. Dr. Cheson's clinical interests focus on the development and evaluation of new therapeutic approaches for hematologic malignancies.


Matthew A. Barish, M.D.
Scientific Advisor
Perceptive Informatics

Dr. Matthew Barish is currently Assistant Clinical Professor, Co-Director of Body Imaging and Director of MRI at Stony Brook University Medical Center. He has contributed extensively to the field of radiology in the areas of 3D image processing, MR cholangiopancreatography and virtual colonoscopy. Dr. Barish is the Co-Founder and former Co-Director of the Dana-Farber/HCC Tumor Imaging Metrics Core Lab, focusing on the standardization of radiologic tumor response assessment. He remains the Director for the International Symposia on Virtual Colonoscopy, which he began in 2000, and the Director of CT Colonography at the ACR Education Center.