The Long, Silent Prelude: Imaging Alzheimer’s Before Symptoms Emerge
Medical imaging plays a pivotal role in understanding Alzheimer’s Disease (AD) during the presymptomatic period when cognitive changes are subtle and difficult to detect. It’s important to stay current on the latest research about how these biomarkers are changing: both in terms of when (stage of the disease) and where (affected areas in the brain) and how these findings could impact your clinical development programs.
This webinar will review how novel imaging and trial designs are improving accessibility and precision in presymptomatic AD research, including:
- How changes in amyloid burden, tau deposition and atrophy can be detected during the presymptomatic phase of AD
- How ultra low-field MRI and rapid MRI techniques can increase accessibility to imaging both in clinical research and in clinical trials
- How new trial designs are needed to define relevant treatment effects in presymptomatic AD
Join us to learn how imaging biomarkers can detect Alzheimer’s decades before symptoms, supporting earlier intervention and innovative trial designs.
Date Tuesday, September 23
10:00 am ET
Presenters:
David Cash, PhD, Sr. Medical Director, Perceptive Imaging
Prof. Cash is an acknowledged expert with 20 years’ experience in neuroimaging of Alzheimer’s Disease and other forms of dementia. He actively participates on various national/international committees, including DIAN, ADNI, GENFI, and has led the ISTAART Neuroimaging PIA, an organization of 1700 neuroimaging researchers working in dementia. His research focuses on identifying early signs & characterizing preclinical stages of dementias and how these changes can better inform clinical trials.
Samuel Lockhart, PhD, Sr. Scientific Director, Perceptive Imaging (Moderator)
Dr. Samuel Lockhart is a neuroscientist with 20+ years’ experience investigating brain health using imaging, cognitive, and biomarker data. He has led imaging biomarker efforts in NIH ADRCs and both academic and industry clinical trials, has 90+ publications in aging and neurodegenerative disease, and is Programs Chair of the ISTAART Neuroimaging PIA. At Perceptive, Sam drives scientific strategy for imaging biomarkers in CNS clinical trials.