PSMA-PET Imaging
PSMA-PET imaging is a powerful tool for prostate cancer drug development, enabling precise tumor localization, assessment of PSMA expression, and the ability to monitor therapeutic efficacy.


With the approvals of several PSMA-targeted tracers and therapeutic agents, the industry is undergoing a renaissance. As the leading provider in PSMA-PET imaging solutions with the largest global footprint in the industry – we are your trusted scientific partner, capable of scaling seamlessly from preclinical studies to early and late-phase registrational trials.
35+
PSMA-PET clinical trials supported
5,500+
PSMA-PET scans analyzed
25+
Preclinical studies supported
Why partner with Perceptive for PSMA-PET imaging clinical trial solutions?
1. End-to-end imaging support, from preclinical research to global Phase 0-4 clinical trials
2. Advanced artificial intelligence (AI) tools for deep learning driven image analysis
3. Trusted partner in radioligand therapy and theranostics
Our imaging core lab team delivers streamlined solutions for PSMA-PET clinical trials, enabling sponsors to execute complex studies efficiently while generating high-quality data for regulatory submissions and therapeutic decision-making.
Clinical Imaging Core Lab Services
- Study Design & Strategy: Expert guidance on imaging endpoints, eligibility criteria, and trial workflows.
- Imaging Site Setup: Scanner and instrumentation setup and image acquisition guidelines provided by experienced board-certified technologists.
- Eligibility & Efficacy Reads: Specialized support for exploratory and established standards like RECIST 1.1, PCWG3, PROMISE, RECIP, PPP
- Multi-Center Coordination: Harmonized imaging protocols and centralized data management across global trial sites.
- AI-Driven Image Analysis: Quantitative PET SUV readouts, lesion segmentation, and total PSMA disease burden assessments.
- Regulatory Compliance: Imaging support for submissions to FDA, EMA, and other regulatory bodies.
- Real-Time Image Access: Secure, cloud-based sharing of images post-QC, enabling sponsors, and designated vendors to access and review imaging data in real time
We help drug developers deliver trials on time, on budget, and with the imaging insights needed to move therapies forward.
Our preclinical imaging solutions set the stage for successful clinical translation. By integrating radiochemistry, biodistribution studies, and tumor-targeting imaging, we enable drug developers to optimize their PSMA-targeted agents with confidence.
Key Preclinical Offerings:
- Radiolabeling and biodistribution studies for lead compound selection.
- Imaging to evaluate tumor targeting, kinetics, and therapeutic potential.
- Development support for PSMA-targeted theranostics.
With expertise across isotopes such as 177Lu, 68Ga, 225Ac, and 18F, our team delivers actionable preclinical insights that accelerate discovery pipelines.
PSMA-PET Imaging and Artificial Intelligence
As the only imaging solutions provider to date to support an FDA submission of quantitative PET data using AI, we bring unmatched expertise to your imaging strategy. Perceptive combines advanced imaging platforms with proprietary AI-driven tools to maximize the value of imaging data. Our analytics support whole-body quantification, lesion co-localization, and detailed response assessments for both preclinical and clinical trials.
Our updated, Automated PSMA Segmentation Tool (available April 2025) offers increased automation and flexibility / sensitivity for faster processing times. The enhanced features of Version 2 include:
- Trained to segment both bone and soft-tissue lesions automatically, significantly reducing human processing time
- Tunable post processing to enable flexibility across different disease stages or tracers\
- Post processing enables robust and dynamic thresholding, and demonstrates flexibility to treat different areas of the body differently, ex. rib lesions v. lumbar lesions
Perceptive’s AI team is continuing to develop cutting edge solutions to advance imaging and image analysis across the clinical space.
Key AI Capabilities:
- Automated lesion segmentation for bone and soft tissue disease, with dynamic thresholding tailored to different tissue types for more accurate and robust data output.
- PET-CT co-registration for precise anatomical and molecular imaging alignment.
- Dosimetry workflows for comprehensive safety assessments.
- Image quality control tailored to trial-specific requirements.
Dosimetry services for PSMA-PET
Perceptive provides comprehensive dosimetry services for the development of radiopharmaceuticals, including PSMA-targeted agents. We support both normal organ and tumor dosimetry through well-established workflows that ensure precision and reliability in whole body, organ and tumor radiation dose assessments. Our in-house team and external collaborators include imaging scientists, PSMA-dual certified radiologists, as well as nuclear medicine physicians, who bring specialized knowledge to every project.
Additionally, we are able to ship imaging phantoms to trial sites, enabling standardized imaging calibration and accurate dose calculations, while our robust phantom analysis further enhances the quality of results.
PSMA Tracer Management Services
Perceptive offers expertise and a dedicated customer-centric team with years of experience in radiopharmacy networks, shipping and handling, transportation logistics and more with regulatory, quality and project manager backgrounds.
Service offerings include but are not limited to:
- Management of network and distribution of different commercial and investigational tracers (PET, SPECT, Antibody, Tau, PSMA)
- Strong partnerships with qualified commercial vendors and contracted manufacturing organizations (CMOs)
- Supporting tracer availability across the globe
- Extensive experience related to onboarding and interaction with hundreds of Imaging Centers (ICs) worldwide, across multiple studies and networks
- Global logistics and transportation expertise
- Invoice reconciliation of dose delivery and processing, escalations and reporting
- Web based electronic dose management tool
With unmatched expertise in PSMA-PET imaging, radioligand therapy, and theranostics, Perceptive empowers drug developers with better prostate cancer biomarkers. From preclinical discovery to late-phase clinical trials, we provide the tools, expertise, and insights to deliver success.
Partner with Perceptive Imaging to Advance PSMA-PET Research
Contact us to learn how our comprehensive imaging solutions can transform your research.