Asset Type: Posters, Imaging, Imaging Core Lab, Additional 
Therapeutic Areas

AI-Driven Instance Segmentation of Cysts in Autosomal Dominant Polycystic Kidney Disease (ADPKD)

AI-Driven Instance Segmentation of Cysts in Autosomal Dominant Polycystic Kidney Disease (ADPKD)

AI-Driven Instance Segmentation of Cysts in Autosomal Dominant Polycystic Kidney Disease (ADPKD)

This poster evaluates AI-driven instance segmentation for automatically identifying and delineating individual kidney cysts in autosomal dominant polycystic kidney disease (ADPKD) on MRI. Researchers compared two AI architectures against radiologist-generated ground truth and found that both supported automated cyst identification, with Mask R-CNN demonstrating stronger overall performance. The findings show the potential of AI-based segmentation to enable scalable cyst burden analysis and longitudinal tracking, supporting exploration of novel imaging biomarkers in ADPKD.

  • Explore how AI can automate individual cyst identification and segmentation, helping address the challenges of manual annotation at scale.
  • Compare the performance of two AI segmentation approaches, Mask R-CNN and MedSAM3, against radiologist-generated ground truth.
  • See the potential for automated cyst tracking over time to support cyst burden analysis and exploration of novel imaging biomarkers in ADPKD.

 

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